Muscimol mechanism of action

Papers broadly covering the Amanita genus.
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Halibut_Acid
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Muscimol mechanism of action

Post by Halibut_Acid » Thu Nov 12, 2020 10:36 pm

@amanitadreamer

I got some time to browse the literature today and have attached a PDF detailing some of the binding activity of muscimol. One quote from the paper: "Molecular modeling studies of GABA, muscimol, and bicuculline support the concept of these three agents acting at the orthosteric site at GABAa receptors in varying active confirmations". The orthosteric site is where endogenous GABA binds in normal function.

There's is some other interesting information in there, but not all necessarily related to muscimol. May be worth a read.
Attachments
Muscimol MOA1.pdf
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