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Decarboxylation through tea preparation

Posted: Tue Jan 05, 2021 11:29 am
by psychem
Not sure if this has been mentioned but this article:

Peng et al. 2006

Says: 'Years later, Nielsen and coworkers independently explored the nonenzymatic decarboxylation of ibotenic acid, reporting that 1 was stable in water even at 37°C overnight and only after its exposure to boiling water at pH extremes over the course of several hours was any decarboxylation to 2 noted'

Suggesting that preparation by making tea even with addition of lemon juice wouldn't decarb any of the ibotenic acid..?

Re: Decarboxylation through tea preparation

Posted: Thu Jan 07, 2021 2:07 am
by amanitadreamer
psychem wrote:
Tue Jan 05, 2021 11:29 am
Not sure if this has been mentioned but this article:

Peng et al. 2006

Says: 'Years later, Nielsen and coworkers independently explored the nonenzymatic decarboxylation of ibotenic acid, reporting that 1 was stable in water even at 37°C overnight and only after its exposure to boiling water at pH extremes over the course of several hours was any decarboxylation to 2 noted'

Suggesting that preparation by making tea even with addition of lemon juice wouldn't decarb any of the ibotenic acid..?
The Austin Patent proved otherwise and is more recent.

Re: Decarboxylation through tea preparation

Posted: Thu Jan 07, 2021 4:56 pm
by Donn
psychem wrote:
Tue Jan 05, 2021 11:29 am
this article
Were you able to read it? Can you provide an link to the accessible full text? It's always interesting to see more on this story. I'm not saying I'm competent to evaluate the full article, if I could see it, but I'm sure not without seeing it.

Re: Decarboxylation through tea preparation

Posted: Thu Jan 14, 2021 1:02 pm
by psychem
The link to the article is here:

https://www.tandfonline.com/doi/full/10 ... -200051704

However you need an institutional log in to access it, if you are unable to I can pm u the pdf as im not sure how to attach a pdf on here!

I believe this is the patent @amanitadreamer was refering to:

https://patentimages.storage.googleapis ... 4084A1.pdf