Mannitol in Amanita muscaria--an osmotic blood-brain barrier disruptor enhancing its hallucinogenic action?

A forum to discuss the psychopharmacology and neuroscience relating to Amanita Muscaria.
Post Reply
User avatar
Aquavitae
Posts: 38
Joined: Tue Nov 05, 2019 11:26 pm
Has thanked: 70 times
Been thanked: 46 times

Mannitol in Amanita muscaria--an osmotic blood-brain barrier disruptor enhancing its hallucinogenic action?

Post by Aquavitae » Wed Nov 20, 2019 5:08 pm

https://www.ncbi.nlm.nih.gov/pubmed/23932733
Abstract
Hypothesis have been made that relatively high level of mannitol present in the tissues of fly agaric (Amanita muscaria) enables more efficient transportation of these active substances into the brain and thus enhance their total activity. It may have been supported by the fact that hallucinogenic effect after A. muscaria consumption is greater than after ingestion of an active substance quantity which the eaten fungi dose contain.
These users thanked the author Aquavitae for the post (total 2):
Splinters and ShardsImme

Post Reply